Promising immunomodulatory effects of selected strains of dairy propionibacteria as evidenced in vitro and in vivo.

نویسندگان

  • Benoît Foligné
  • Stéphanie-Marie Deutsch
  • Jérôme Breton
  • Fabien J Cousin
  • Joëlle Dewulf
  • Michel Samson
  • Bruno Pot
  • Gwénaël Jan
چکیده

Immunomodulatory properties of 10 dairy propionibacteria, analyzed on human peripheral blood mononuclear cells (PBMCs), revealed a highly strain-dependent induction of anti-inflammatory cytokine interleukin 10 (IL-10). Two selected strains of Propionibacterium freudenreichii showed a protective effect against two models of colitis in mice, suggesting a probiotic potential predicted by immune-based selection criteria for these cheese starter bacteria.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 76 24  شماره 

صفحات  -

تاریخ انتشار 2010